Indications for Anticoagulant and Antiplatelet Therapy

About the Course:
Because of the high prevalence of cardiovascular disease, it is likely that many nurses and advanced practice nurses (APN) will encounter patients using antiplatelet and anticoagulant medications in their practice. Furthermore, some clinicians working in specialized fields will have patients requiring thrombolytic therapy. Although these medications are quite useful and play an important role in contemporary medical practice, there are potentially dangerous adverse events and hazards associated with their use. In order to best balance these positive and negative attributes, it is critical that nurses develop an understanding of how they work and how to optimize the management of their patients who depend on them. This educational program is designed to provide an overview of the safe use of antiplatelet, anticoagulant, and thrombolytic medications.

Learning Outcomes:
Upon completion of this course, the learner will be able to:
  • Describe aspirin’s mechanism of action.
  • Distinguish between the efficacy of aspirin for the prevention of primary versus secondary cardiovascular events.
  • Identify one population of patients in which aspirin is contraindicated.
  • Understand the meaning of the term prodrug as it applies to clopidogrel.
  • Appreciate one advantage of low-molecular weight heparin compared to unfractionated heparin.
  • State a contraindication to the use of low-molecular weight heparin.
  • Name a type of food that should be consumed consistently, or not at all, by patients using warfarin.
  • State an off-label use of Tenecteplase.
  • Identify the most common adverse event associated with antiplatelet, anticoagulant, and thrombolytic medications.

About the Author:
Bradley Gillespie, PharmD, Trained as a clinical pharmacist, has practiced in an industrial setting for the past 25+ years. His initial role was as a Clinical Pharmacology and Biopharmaceutics reviewer at the U.S. Food and Drug Administration (FDA), followed by 20 years of leading early development programs in the pharma/biotech/ nutritional industries. In addition to his industrial focus, Dr. Gillespie remains a registered pharmacist and enjoys mentoring drug development scientists and health professionals, leading workshops, and developing continuing education programs for pharmacy, nursing, and other medical professionals.

How to Receive Credit:
  • Read the entire course online or in print which requires a 3-hour commitment of time.
  • Complete the Self-Assessment Quiz Questions either integrated throughout or all at the end of the course.
    • These questions are NOT GRADED. The questions are included to help affirm what you have learned from the course.
    • The correct answer is shown after the question is answered. If the incorrect answer is selected, a Rationale for the correct answer is provided.  
  • At the end of the course, answer the Yes/No Affirmation question to indicate that you have completed the educational activity.
  • Specific to Florida: A mandatory Final Examination with a passing score of 70% or higher is required. Exam questions link content to the course Learning Objectives as a method to enhance individualized learning and material retention. 
  • If requested, provide required personal and payment information. 
  • Complete the mandatory Nursing Course Evaluation. 
  • Print your Certificate of Completion.

Bradley Gillespie, PharmD  has disclosed  he does not have a financial relationship with ineligible companies.
Planners, faculty, and others in control of content (either individually or as a group) have no relevant financial relationships with ineligible companies.

Sponsorship/Commercial Support and Non-Endorsement
It is the policy of Colibri Healthcare, LLC not to accept commercial support. Furthermore, commercial interests are prohibited from distributing or providing access to this activity to learners. 

The information provided in this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition ©2022: All Rights Reserved. Materials may not be reproduced without the expressed written permission or consent of Colibri Healthcare, LLC. The materials presented in this course are meant to provide the consumer with general information on the topics covered. The information provided was prepared by professionals with practical knowledge of the areas covered. It is not meant to provide medical, legal, or professional advice. Colibri Healthcare, LLC recommends that you consult a medical, legal, or professional services expert licensed in your state. Colibri Healthcare, LLC has made all reasonable efforts to ensure that all content provided in this course is accurate and up-to-date at the time of printing but does not represent or warrant that it will apply to your situation nor circumstances and assumes no liability from reliance on these materials. Quotes are collected from customer feedback surveys. The models are intended to be representative and not actual customers. 

Course Verification
Every reasonable effort has been made to ensure that the content in this course is balanced and unbiased.