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Disciplines: Pharmacists
Hours: 3 Contact Hours
Author(s): Diana M. Sobieraj, PharmD, BCPS
Peer Reviewer(s):
  • Leanne Henry Fowler, DNP, AGACNP-BC, CCRN, CNE
  • Abir Kanaan, PharmD, RPh
Item#: Y8010
Contents: 1 Course Book (42 pages)
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Parenteral Anticoagulant Therapy: Implications for Patient Management

Price $12.95
Item # Y8010
When available, the Online Course format is included with the hard copy, eBook, or audio book formats!

Start Date: September 16, 2016

Expiration Date: September 16, 2019


Anticoagulants are central to the management of cardiovascular and thrombotic conditions. Parenteral anticoagulants are particularly important in acute care situations given their fast onset of action. They are indicated for the management of acute coronary syndromes (ACS), in the treatment and prevention of venous thromboembolism (VTE), and in the management of heparin-induced thrombocytopenia (HIT). With the variety of oral anticoagulants now available, it is also important that pharmacists recognize the changing role of parenteral anticoagulants when the indications overlap with those of oral therapy. Furthermore, they must be able to safely transition patients from parenteral to oral anticoagulants.

This course is designed for pharmacists who are involved in decision making for parenteral anticoagulant selection or who provide care for patients who have already been prescribed a parenteral anticoagulant. The purpose of this course is to increase pharmacists’ knowledge of parenteral anticoagulants so that they can identify patients in whom therapy is indicated, assist in selecting the most appropriate option, and monitor and counsel the patient.

The focus of this course is on parenteral anticoagulants, their most pertinent prescribing information, and strategies for effective patient monitoring and counseling. This course begins with an overview of current practice guidelines for VTE prevention and treatment, HIT, and ACS. Then, an overview of the prescribing information for each associated parenteral anticoagulant follows, including strategies for reversal, patient monitoring, and counseling when applicable.


Universal Activity Number (UAN) - 0607-0000-16-008-H01-P

Type of Activity - Knowledge

Topic Designator - 01 – Disease State Management/Drug Therapy

Course Objectives

  • Identify the current role of parenteral anticoagulants in the management of patients with venous thromboembolism (VTE) and for VTE prophylaxis, acute coronary syndromes (ACS), and heparininduced thrombocytopenia (HIT).
  • Compare and contrast parenteral anticoagulants, their respective pharmacologic class, and their approved indications.
  • Identify pertinent contraindications, side effects, drug interactions, monitoring parameters, and patient counseling points for parenteral anticoagulants.
  • Identify reversal agents for parenteral anticoagulants.


Diana M. Sobieraj, PharmD, BCPS, earned her doctor of pharmacy degree from the University of Rhode Island and subsequently completed a pharmacy practice residency at Hartford Hospital/The University of Connecticut (UCONN) School of Pharmacy. After her training, Dr. Sobieraj joined the faculty at UCONN School of Pharmacy, where she has worked for the past 8 years. Currently, Dr. Sobieraj is an assistant professor in the Department of Pharmacy Practice in the tenure track. Her scholarly interests focus on comparative effectiveness and health outcomes research of anticoagulants and the treatment and prevention of thrombosis. Dr. Sobieraj has more than 40 publications in the peer-reviewed literature, including journals such as the Annals of Internal Medicine, Journal of the American Geriatrics Society, International Journal of Cardiology, and Thrombosis Research. Dr. Sobieraj is a member of the American College of Clinical Pharmacy, the current Secretary/Treasurer of the American College of Clinical Pharmacy Health Outcomes PRN, and a member of the Community Advisory Panel of the American College of Clinical Pharmacy Practice-Based Research Network.


Leanne Henry Fowler, DNP, AGACNP-BC, CCRN, CNE, graduated with a baccalaureate of science in nursing degree from Southern University in Baton Rouge, Louisiana, and a doctorate in nursing practice (DNP) specializing in nursing education and as an adult/gerontology acute care nurse practitioner from the University of South Alabama in Mobile. She conducted a successful quality improvement project for her DNP project titled Preventing Oversedation in the Mechanically Ventilated Adult via Interprofessional Implementation of the RASS Tool. She has 15 years of critical care nursing experience, 8 years of nursing education experience, 2 years as a board-certified adult/gerontology acute care nurse practitioner in hospital medicine, and 6 months in infectious diseases. She is ranked as an instructor at the LSU Health Sciences Center’s School of Nursing, where she is the course coordinator for the critical care course in the baccalaureate program and the BSN to DNP academic coordinator for the Adult-Gerontology Acute and Emergency Care Nurse Practitioner concentration. She is an active member in several professional organizations, including the American Association of Nurse Practitioners (nationally, as well as in the state and local chapters), American Association of Critical-Care Nurses (nationally, as well as the local chapter), Society of Critical Care Medicine (nationally, as well as the regional chapter), National League for Nursing, National Organization of Nurse Practitioner Faculty, and the Epsilon Nu chapter of Sigma Theta Tau.

Abir Kanaan, PharmD, RPh, is an associate professor of pharmacy practice at Massachusetts College of Pharmacy and Health Sciences (MCPHS) University. She joined the university in 2005, after completing a postgraduate pharmacy practice residency at University of Massachusetts Memorial Medical Center in Worcester, Massachusetts. Dr. Kanaan also holds an adjunct faculty position in the Department of Medicine at the University of Massachusetts Medical School. She is affiliated with the Meyers Primary Care Institute, where she is involved in several research projects pertaining to medication safety in the outpatient setting. Dr. Kanaan serves as a co-director and preceptor for the pharmacy fellowship program in Medication Safety, Quality and Informatics at Saint Vincent Hospital in Worcester. Dr. Kanaan is also the Postgraduate Education Committee Program Coordinator for the Worcester and Manchester campuses at MCPHS University. Dr. Kanaan’s practice site is Saint Vincent Hospital in the Coronary Intensive Care unit. She started and currently leads the hospital’s anticoagulation monitoring program.

  • Courses must be completed on or before the expiration date noted in the course description above.
  • You must score 75% or higher on the final exam and complete the course evaluation to pass this course and have your record transmitted to your NABP e-Profile account.
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  • All persons involved in the planning and development of this course have disclosed no relevant financial relationships or other conflicts of interest related to the course content.