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  • Advanced Practice Nursing
Hours: 2 Contact Hours (2 Pharm Hours)
  • William L. Baker, PharmD, FCCP, FACC, BCPS-AQ Cardiology
  • Leanne H. Fowler, DNP, MBA, AGACNP-BC
Peer Reviewer(s): Abir Kanaan, PharmD, RPh
Item#: N1749
Contents: 1 Course Book (30 pages)
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Thrombolytic Therapy: Implications for Advanced Practice Nursing

Price $17.95
Item # N1749
High-Level Content
When available, the Online Course format is included with the hard copy, eBook, or audio book formats!

Release Date: December 21, 2016

Expiration Date: December 31, 2019

Thrombolytic medications are commonly used to treat thromboembolic disorders, including acute ischemic cerebrovascular accident, ST-elevation myocardial infarction, and pulmonary embolism. These patient populations represent individuals at high risk of morbidity and mortality. The treatment of these conditions is often time sensitive and requires quick action to be taken. Thus, a working knowledge of thrombolytic drugs is important for nurses who may manage these patients. In addition, there are critical differences in terms of the pharmacology and pharmacokinetics of these agents that leads one option to be superior to another or drives the patient monitoring that needs to occur.

All clinicians play an important role in managing patients with these conditions who are eligible for high-risk pharmacologic therapies, such as thrombolytics. Specific knowledge of the general information and caveats associated with thrombolytic therapy is vital for optimal patient care outcomes to be achieved. This course is designed for nurses (registered and advanced practice nurses) who prescribe for or provide care to patients being considered for thrombolytic medications. The purpose of this course is to increase nurses’ knowledge of thrombolytic medications so that they can identify the optimal therapy and safely use these medications.


This course is an extract of, and should not be taken in conjunction with N1752 - Anticoagulant, Antiplatelet, and Thrombolytic Therapies: Implications for Advanced Practice Nursing.

Course Objectives

  • Identify the relevant pharmacokinetic and pharmacodynamics properties of thrombolytics.
  • Apply the contemporary role of thrombolytics to the management of a patient diagnosed with acute ischemic stroke.
  • Describe evidence supporting the use of thrombolytics in acute myocardial infarction.
  • Describe the most appropriate population to receive thrombolytics for treating acute pulmonary embolism.
  • Describe key patient selection and monitoring that can ensure optimal patient outcomes.
  • Describe how the nurse can use this information to optimize patient outcomes.


William L. Baker, PharmD, FCCP, FACC, BCPS-AQ Cardiology, is an Assistant Professor of Pharmacy Practice at the University of Connecticut (UConn) School of Pharmacy in Storrs, Connecticut. Dr. Baker received his BS in Pharmacy Studies and Doctor of Pharmacy (PharmD) degrees from the UConn School of Pharmacy in 2000 and 2002, respectively. After being in clinical practice for a number of years, he completed a 2-year cardiovascular pharmacology and outcomes research fellowship at Hartford Hospital in Hartford, Connecticut (2006-2008). He has been on faculty with the UConn School of Pharmacy since 2009.

Dr. Baker is a member of a number of pharmacy and cardiology organizations, including the American College of Clinical Pharmacy, American Heart Association, and American College of Cardiology. His clinical experience has focused on caring for adult patients with advanced heart disease who require mechanical therapies or cardiac transplantation. He is the author of more than 100 peer-reviewed publications and frequently presents his research at national/international pharmacy and cardiology conferences. Dr. Baker teaches cardiovascular pharmacology and therapeutics in the UConn School of Pharmacy and holds adjunct appointments as Assistant Professor with both the UConn School of Medicine and Uuconn Graduate School.

Leanne H. Fowler, DNP, MBA, AGACNP-BC, CCRN, CNE, graduated with a baccalaureate of science in nursing degree from Southern University in Baton Rouge, Louisiana, and a doctorate in nursing practice (DNP) specializing in nursing education and as an adult/gerontology acute care nurse practitioner from the University of South Alabama in Mobile. She conducted a successful quality improvement project for her DNP project titled Preventing Oversedation in the Mechanically Ventilated Adult via Interprofessional Implementation of the RASS Tool. She has 15 years of critical care nursing experience, 8 years of nursing education experience, 2 years as a board-certified adult/gerontology acute care nurse practitioner in hospital medicine, and 6 months in infectious diseases. She is ranked as an instructor at the LSU Health Sciences Center’s School of Nursing, where she is the course coordinator for the critical care course in the baccalaureate program and the BSN to DNP academic coordinator for the Adult-Gerontology Acute and Emergency Care Nurse Practitioner concentration. She is an active member in several professional organizations, including the American Association of Nurse Practitioners (nationally, as well as in the state and local chapters),American Association of Critical-Care Nurses (nationally, as well as the local chapter), Society of Critical Care Medicine (nationally, as well as the regional chapter), National League for Nursing, National Organization of Nurse Practitioner Faculty, and the Epsilon Nu chapter of Sigma Theta Tau.


Abir Kanaan, PharmD, RPh, is an Associate Professor of Pharmacy Practice at MCPHS University. She joined the university in 2005 after completing a postgraduate pharmacy practice residency at UMass Memorial Medical Center in Worcester, Massachusetts. Dr. Kanaan also holds an adjunct faculty position in the Department of Medicine at the University of Massachusetts Medical School. She is also affiliated with the Meyers Primary Care Institute, where she is involved in several research projects pertaining to medication safety in the outpatient setting. Dr. Kanaan also serves as a codirector and preceptor for the pharmacy fellowship program in Medication Safety, Quality and Informatics at Saint Vincent Hospital in Worcester, Massachusetts. Dr. Kanaan is also the Postgraduate Education Committee Program Coordinator for the Worcester and Manchester campuses at MCPHS University. Dr. Kanaan’s practice site is Saint Vincent Hospital in the Coronary Intensive Care unit. She also started and currently leads the hospital’s anticoagulation monitoring program.

  • Courses must be completed on or before the expiration date noted in the course description above.
  • You must score 75% or higher on the final exam and complete the course evaluation to pass this course and receive a certificate of completion.
  • Through our review processes, Western Schools ensures that this course content is presented in a balanced, unbiased manner and is free from commercial influence. It is Western Schools’ policy not to accept commercial support.
  • All persons involved in the planning and development of this course have disclosed no relevant financial relationships or other conflicts of interest related to the course content.